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Effect of lactate on demineralization of synthetic hydroxyapatite

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Abstract


Many kinds of soluble calcium salts such as calcium lactate are known to reduce the enamel demineralization. In this study, calcium lactate was tested for its effect on the demineralization process of hydroxyapatite. Synthetic hydroxyapatites
were
used
as a standardized material instead of human enamel which is rarely heterogenous. And, for the purpose of hydroxyapatite demineralization, lactic acid was used. By comparing the weight of hydroxyapatite pre-demineralization and
post-demineralization, it
was possible to examine the effect of calcium lactate on demineralization.
The weight of demineralized hydroxyapatite was reduced by about 46% and 59% with 20mM and 40mM calcium lactate respectively. In conclusion, low concentrations of calcium lactate showed an inhibitory effect on the demineralization of synthetic
hydroxyapatite.

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